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International Tables for Crystallography

Volume F: Crystallography of biological macromolecules

Edited by Michael G. Rossmann, Department of Biological Sciences, Purdue University, West Lafayette, Indiana 47907, USA and Eddy Arnold, Center for Advanced Biotechnology and Medicine, Department of Chemistry, Rutgers University, 679 Hoes Lane, Piscataway, NJ 08854, USA



[CoverF]

First edition July 2001

808+xxiv pp.

ISBN 0-7923-6857-6

Price:
EUR 311.00/USD 289.00/GBP 181.75 for institutions,
EUR 155.50/USD 144.50/GBP 90.75 for individuals



Reduced-rate copies are for personal use only and are not to be placed at the disposal of any library.

International Tables for Crystallography, Volume F, Crystallography of biological macromolecules is an expert guide to macromolecular crystallography for the modern structural biologist. It was commissioned by the International Union of Crystallography in recognition of the extraordinary contributions that knowledge of macromolecular structure has made, and will make, to the analysis of biological systems, from enzyme catalysis to the workings of a whole cell, and to the growing field of structural genomics. The volume covers all stages of a crystallographic analysis from the preparation of samples using the techniques of molecular biology, through crystallization, diffraction data collection, phase determination, structure validation and structure analysis.

Although the book is written for experienced scientists, it is recognized that the reader is more likely to be a biologist interested in structure than a classical crystallographer interested in biology. Thus there are chapters on the fundamentals, history and current perspectives of macromolecular crystallography, as well as the availability of useful programs and databases including the Protein Data Bank. Each chapter is written by an internationally recognized expert.

Volume F was recently reviewed by C. W. Carter Jr [Structure (2002). 10, 289] and J. J. Müller [Z. Kristallogr. (2002). 217, 627-628].


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